I decided to take a ride on this I Want Sandy service. 
Reading over the description of it, especially the information about conversational interfaces, I have run a few things through it and I think it could be very useful. Key items I like:
- getting reminders to my phone, which detaches me from email/computer/home
- having events/appointments returned as iCal events, all ready to go into a calendar
- and the conversation tone (“Wishing I could fax you a doughnut,”) makes it worth reading the replies.
My good friends at the blood center already send me my appointments via iCal/Google calendar, and that helps. But a reminder service with features like contact tracking and a snooze feature (“Remind me in 2 days”) borders on the magical.
I hate all the organizational systems I have tried, though I realize that simply projection: what I really hate is my inconsistency with them.
It’s free, so no commitment, no wasted money on systems and no wasted time learning someone else’s way of doing things. Can’t beat that. And could the icon be any cuter?
[via Sandy, remind me about that New Year’s resolution @sms]